Dynamics of the Epigenetic Landscape During Erythroid Differentiation after GATA 1 Restoration Running head : Chromatin state profiles precede gene regulation
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چکیده
Weisheng Wu, Yong Cheng, Cheryl A. Keller, Jason Ernst, Swathi Ashok Kumar, Tejaswini Mishra, Christapher Morrissey, Christine M. Dorman, Kuan-Bei Chen, Daniela Drautz, Belinda Giardine, Yoichiro Shibata, Lingyun Song, Max Pimkin, Gregory E. Crawford, Terrence S. Furey, Manolis Kellis, Webb Miller, James Taylor, Stephan C. Schuster, Yu Zhang, Francesca Chiaromonte, Gerd A. Blobel, Mitchell J. Weiss, and Ross C. Hardison
منابع مشابه
Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration.
Interplays among lineage-specific nuclear proteins, chromatin modifying enzymes, and the basal transcription machinery govern cellular differentiation, but their dynamics of action and coordination with transcriptional control are not fully understood. Alterations in chromatin structure appear to establish a permissive state for gene activation at some loci, but they play an integral role in ac...
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تاریخ انتشار 2011